Behcet Disease

A chronic inflammatory disorder characterized by recurrent oral ulcers and variable genital, eye, skin, vascular, neurologic or gastrointestinal involvement.
Its course is relapsing, and the pattern of organ involvement differs considerably between affected individuals.
Diagnosis is clinical because no single laboratory test confirms the disease; ophthalmic and vascular assessment may be particularly important.
Treatment is matched to organ severity and can include topical therapy, colchicine, corticosteroids, immunosuppressants or biologic agents.
Eye, neurologic and major-vessel disease require timely specialist management because they can threaten vision, function or life.