Bence Jones Protein
Free monoclonal immunoglobulin light chains detectable in urine and associated especially with plasma-cell disorders such as multiple myeloma.
Free monoclonal immunoglobulin light chains detectable in urine and associated especially with plasma-cell disorders such as multiple myeloma.
Excess light chains are small enough to pass through the kidney filter and can contribute to renal tubular injury.
Urine protein electrophoresis, immunofixation and serum free-light-chain testing are used to identify and characterize the abnormal protein.
Management is directed at the underlying plasma-cell or lymphoid disorder rather than at the urinary protein itself.
Its detection can support diagnosis, disease assessment and monitoring when interpreted with marrow, blood and imaging findings.
Excess light chains are small enough to pass through the kidney filter and can contribute to renal tubular injury.
Urine protein electrophoresis, immunofixation and serum free-light-chain testing are used to identify and characterize the abnormal protein.
Management is directed at the underlying plasma-cell or lymphoid disorder rather than at the urinary protein itself.
Its detection can support diagnosis, disease assessment and monitoring when interpreted with marrow, blood and imaging findings.
This information is for general awareness only and is not medical advice. Consult a doctor for any health concern.